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Data Element Name

Definition

Sample ValuesMustSupport

Cardinality

USCDI

USCDI Element

US Core Profile / FHIR Resource

US Core Profile / FHIR Element

eICR Profile.element

HCV Test

 

Anti-HCV, HCV RNA, HCV genotype

Laboratory

Tests

US Core Laboratory Result Observation Profile

code

US Core Laboratory Result Observation Profile.code

Hepatitis C Diagnosis

 Acute, Chronic

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

HCV Treatment

 

Prescribed direct-acting antiviral (DAA)

Medication

Medication

US Core Medication Request Profile

medication[x]

eICR Composition.section:slicePlanOfTreatmentSection.entry:sliceUSCoreMedicationRequest.medication[x]

HCV Cure (SVR)

Negative HCV RNA level 6 months after starting treatment

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value

Pregnancy Status*

If pregnant, infants of HBV or HCV infected women should be tested for infection (see disease-specific guidelines)

HCG result positive

n/a

 

Pregnancy Status Observation

value[x] 

Pregnancy Status Observation.value[x]

Last Menstrual Period

 

 

n/a

 

Last Menstrual Period

valueDateTime

Last Menstrual Period.valueDateTime

Pregnancy Outcome

 

 

n/a

 

Pregnancy Outcome Observation

valueCodeableConcept

Pregnancy Outcome Observation.valueCodeableConcept

Gestational Age at Outcome

 

 

n/a

 

Pregnancy Status Observation

component:sliceEstimatedGestationalAgeOfPregnancy.valueQuantity

Pregnancy Status Observation.component:sliceEstimatedGestationalAgeOfPregnancy.valueQuantity

Infant Born with Neonatal Abstinence Syndrome (NAS)

 

 

Problems

n/a

US Core Condition Profile

code 

eICR Condition.code

Injected Drug Use (ever)

 

 

Clinical Notes?

 History & Physical

US Core Document Reference Profile

text

Current Drug Use

 

 

Clinical Notes?

 History & Physical

US Core Document Reference Profile

text

SUD/OUD Diagnosis

 

Date of diagnosis*

Date of test result confirming infection

Problems

n/a

US Core Condition Profile

onsetDateTime

eICR Condition.onset[x]

Date of illness onset*

Date of the first sign or symptom of hepatitis

Problems

n/a

US Core Condition Profile

onsetDateTime

eICR Condition.onset[x]

Presence of symptoms of acute hepatitis*

Verifies case definition

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

Presence of jaundice*

Verifies case definition

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

ALT level*

Verifies case definition

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

HCV Treatment

An RXNORM code for HCV medication is present
(NOTE: Ribavirin or interferon alone do not qualify as HCV treatment; they must be prescribed in combination with each other or with a direct-acting antiviral on the med list)

Medication

Medication

US Core Medication Request Profile

medication[x]

eICR Composition.section:slicePlanOfTreatmentSection.entry:sliceUSCoreMedicationRequest.medication[x]

HCV Cure (SVR)

Negative HCV RNA level 6 months after starting treatment

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value

anti-HCV*

anti-HCV positive test results require confirmation by an additional more specific assay or for anti-HCV, a S/CO ratio ≥3.8.

Verifies case definition. Determine all results (positive and negative).

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

Pregnancy Status*

If pregnant, infants of HBV or HCV infected women should be tested for infection (see disease-specific guidelines)

n/a

 

Pregnancy Status Observation

value[x] 

Pregnancy Status Observation.value[x]

SUD/OUD Diagnosis

 

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

MAT Prescribed

 

 

Assessment and Plan of Treatment?

 n/a

US Core Medication Request Profile

medication[x]

eICR Composition.section:slicePlanOfTreatmentSection.entry:sliceUSCoreMedicationRequest.medication[x]

MAT Administered

RxNorm or NDC codes

Patient Name

 Medication

Patient Demographics

 

Medication Administration

medication[x] 

Medication Administration.medication[x]

Patient Name

 

 

Patient Demographics

First Name

Last Name

US Core First Name

Last Name

US Core Patient Profile

name.given

name.family

eCR Patient.name

Patient Address

 

 

Patient Demographics

Current Address

US Core Patient Profile

address

eCR Patient.addressPatient Age

Date of birth*

Core variables (NEDSS standards)

 

n/a

 

Calculated from

Patient Demographics

Date of Birth

US Core Patient Profile

birthDate

eCR Patient.birthDate

Patient Sex

Core variables (NEDSS standards) 

Patient Demographics

Birth Sex

US Core Patient Profile

 us-core-birthsex

eCR Patient.us-core-birthsex

Patient Race

Core variables (NEDSS standards)

 

Patient Demographics

Race

US Core Patient Profile

us-core-race

eCR Patient.us-core-race

Patient Ethnicity

Core variables (NEDSS standards) 

Patient Demographics

Ethnicity

US Core Patient Profile

us-core-ethnicity

eCR Patient.us-core-ethnicity

Origin of report*

Site requesting viral hepatitis testing 

n/a

 

eICR Encounter.location.eICRLocation.name

State of report*

Core variables (NEDSS standards) 

n/a

 

eICR Encounter.location.eICRLocation.address.state

County of report*

Core variables (NEDSS standards)

 

n/a

 

eICR Encounter.location.eICRLocation.address.district

Zip code of report*

Core variables (NEDSS standards)

 

n/a

 

eICR Encounter.location.eICRLocation.address.postalCode

Date of birth*

Core variables (NEDSS standards)

 

Patient Demographics

Date of Birth

US Core Patient Profile

birthDate

eCR Patient.birthDate

Date of illness onset*

First sign or symptom of hepatitis

 

Problems

n/a

US Core Condition Profile

onsetDateTime

eICR Condition.onset[x]

Presence of symptoms of acute hepatitis*

Verifies case definition

 

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

Presence of jaundice*

Verifies case definition

 

Problems

n/a

US Core Condition Profile

code

eICR Condition.code

ALT level*

Verifies case definition

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

Hospitalization for hepatitis*

If yes, verify dates of hospitalization

 

n/a

 

US Core Encounter Profile

hospitalization

eICR Encounter.hospitalization

Hospitalization for hepatitis dates*

 

 

n/a

 

US Core Encounter Profile

period

eICR Encounter.period

Death from hepatitis*

If yes, review death certificate and medical records to rule out other potential causes of death and to confirm acute liver failure as the cause of death

 

n/a

 

Condition

outcome (extension)

IgM anti-HAV*

Verifies case definition. Determine all results (positive and negative).

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

HBsAg*

HBsAg positive test results require confirmation by an additional more specific assay

 

Verifies case definition. Determine all results (positive and negative).

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

IgM anti-HBc*

Verifies case definition. Determine all results (positive and negative).

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

anti-HCV*

anti-HCV positive test results require confirmation by an additional more specific assay or for anti-HCV, a S/CO ratio ≥3.8.

Verifies case definition. Determine all results (positive and negative).

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

anti-HDV*

Verifies case definition. Determine all results (positive and negative).

 

Laboratory

Values/ Results

US Core Laboratory Result Observation Profile

value[x]

US Core Laboratory Result Observation Profile.value[x]

Date of diagnosis*

Date of test result confirming infection

 

Problems

n/a

US Core Condition Profile

onsetDateTime

eICR Condition.onset[x].address.postalCode

Hospitalization for hepatitis*

If yes, verify dates of hospitalization

n/a

 

US Core Encounter Profile

hospitalization

eICR Encounter.hospitalization

Hospitalization for hepatitis dates*

 

n/a

 

US Core Encounter Profile

period

eICR Encounter.period

Death from hepatitis*

If yes, review death certificate and medical records to rule out other potential causes of death and to confirm acute liver failure as the cause of death

n/a

 

Condition

outcome (extension)

US Core Condition.category (coming soon)

Table 3. Hepatitis C Data Elements

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